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Letter One The New Nutrition Paradigm by Rayburne W Goen, MD, FACP, FACC. December 21, 2001 The New Nutrition and Doubting Doctors Dear Doctor: Thank you for allowing me this opportunity to introduce you to a monumental discovery in Healthcare, only recently acknowledged (1996) in Medical Journals and Textbooks. When I first heard about Glyconutritients 2-1/2 years ago, I called it "Hogwash", and declared anyone who claimed that oral administration of these supplements was of striking benefit to people suffering from a long list of unrelated diseases or ailments was a QUACK! In the same class as all the others making such claims for relief of a multitude of ailments, whatever the modality, so blatantly proclaimed and touted in numerous brochures and catalogs in the daily mail. I was closed-minded-- call it skeptical, dubious, or cynical- as you and the rest of our Medical profession would have been, and are. I was, however, receptive enough to read the pertinent Medical Journals supplied to me, and I must admit I was a little jarred at the implications of what I read. I began to look into what turned out to be an overwhelming amount of related literature: Carbohydrate Metabolism is suddenly a hot subject--over 20,000 papers in Medline 1996-1998, and an equal number since. Most of them are in specialty Research Journals that we as practicing physicians do not take or read- nor readily understand! The Clinical articles published thus far have been mainly retrospective: case reports of a series of patients with a major disease, and with suspiciously high percentages of positive results. I read many of these articles, but I could not believe they could be documenting something so fundamentally powerful, as that a mere food supplement could correct a deficiency in our diet so vitally important as to be the mechanism of all cellular communication in our body! I was already well versed in that kind of hype! I had previously tried, on myself, enthusiastically at first, the highly touted Glucosamine, Chondroitin Sulfate, Cetyl Myristoleate, MSM, SAM-e, Blue Green Algae, Alfalfa Tea, Olive Leaf Extract, Colloidal Silver: -- each with lots of “ink” but not one helped me in any way. I proposed to try (surreptitiously-“don’t tell anybody”) Glyconutrients for a list of 21 ailments I could identify in myself, rated in severity from 1-10, attributable mostly to "old age" (I was 85 years old at the time). I was not neurotic-- just trying to be scientific. None of these completely disabled me, except Arthritis of knees, which required aspiration of fluid and instillation of a Cortisone, Depo Medrol, more and more frequently, eventually about every 3 months for one, then the other knee.Then I would again be functional; and I had a Peripheral Neuropathy which impaired my balance and walking, and sleep because of restless legs. Within 4 months, I became symptom-free of 20 of these 21 complaints: the two mentioned, and a right shoulder rotator cuff tear, low back pain, cervical disc with left C-5 radiculopathy, inflammatory osteoarthritis of hands (I could not shake hands without hurting the next 3 days), hypertension (190/105), hypercholesterolemia (320mg) since in my 30’s, nocturia 4-6x per night, urinary urgency incontinence, prostate cancer, developing cataract left eye, etc. I was able to discontinue all the 6 prescribed drugs, and all over-the-counter, except 1 aspirin every other day (I had a Coronary in 1990, after which I began this). The drugs had been effective to a degree, but all had side effects that were either disagreeable or intolerable. That result was not enough to convince me. This had to be some sort of “fluke”! I resolved I could disprove this “stuff” by persuading a “know-it-all” relative who scoffed at the idea of taking supplements like these for his refractory Raynaud's Syndrome (cold-sensitive fingers that turned purple and agonizingly painful upon exposure); uncontrolled Diabetes type 2 with serious adverse effects from Insulin and oral anti-diabetes drugs; Hypercholesterolemia and Diabetic Peripheral Neuropathy, worsened by all “statin” drugs for cholesterol reduction. He was scheduled for replacement surgery of both knees, each of which had been operated twice for old injuries and loss of cartilage, poorly responding to NSAID drugs, and with intolerable side effects. He had stated he was going to discontinue all the above drugs--- he had rather died than live this miserably. I reminded him that dying is an easy out, but that he might not die, but be disabled by Heart Attack, Stroke, Amputations, or Renal failure and Dialysis. I managed to induce him to try Glyconutritionals for 4 months, with the assurance they absolutely could not harm him. He reluctantly agreed...Three weeks later he reported he was free of pain and paresthesias, was having normalized blood sugars on just the one oral anti-diabetes drug he had continued (but that previously had not controlled the high blood sugar) His vision and mental clarity were strikingly improved. He neglected, however, to reorder the supplements, and the symptoms all recurred within 2 weeks. Upon resumption of the supplements, the symptoms again abated. Koch’s postulates fulfilled!! I still was not convinced! I did cautiously offer Glyconutrients to several other former patients, including 2 refractory diabetics with complications, with similar salutary effects. I was nearly convinced after almost a year of results that I could only describe as incredible! So---- I gave Glyconutritionals to Zondra, a patient whom I had “doctored” for 50 years with Muscular Dystrophy, Spinal Atrophy type. (Her brother had died at age 13 with Duchenne type MD). She was total care since age 2 years; unable to do anything for herself; had impairment of swallowing; and was on Oxygen 24 hours daily. She was able to do some ceramics painting, with her right arm supported on a table, for 2 hours, twice a week. 4 months after starting glyconutrients, she could, for the first time in 50 years, feed herself, brush her teeth, scratch her nose, and is now off Oxygen for 3-4 hours daily. She can now swallow well, and she can paint 6-8 hours per day, 6 days a week! She states “I have so much energy I could do more, but know I should rest some, whether I feel the need or not!” She has sustained this improvement, and for the first time ever she has not been treated or hospitalized for respiratory failure or infection in over a year, despite a Flu epidemic disabling two of her Nurses and her room mate! Bill, a former Surgical Technician in the Service, developed Type 2 Diabetes after returning from overseas in the 80’s. When originally diagnosed, his blood sugars were in the 900’s and remained uncontrollably high (above 500) for many years, despite multiple injections of regular Insulin up to 200 units daily, plus Ultra-Lente (long acting) Insulin 120 Units daily. He exhibited Retinopathy, with bleeding inside both eyes requiring years of Laser cautery therapy every 3 months, which provided some improvement but could not prevent subsequent recurrences. He developed Peripheral Neuropathy of both legs and arms with complications of Diabetic Ulcers on his legs and feet, for which amputation was advised. This he refused, but searched the internet to find a possible relief. He experienced considerable muscle deterioration, with Claudication (leg cramps) and Angina on attempting to walk half a block. He gained weight, up to 330 lbs, with the inactivity. Despite being on multiple anti-hypertension medications, his blood pressure for years averaged 200/115. He developed arthritis, with difficulty doing anything with his hands. After 4 years, and requests from a Podiatrist, his Physical Therapists, a Neurologist, and a Health South Rehab Doctor, he finally obtained HMO authorization for an electrified “scooter” which enabled him to get up and around… In the early 90’s, over a 3-4 months time period, he had a series of strokes and 3 TIA’s. He was diagnosed Sleep Apnea, complicated by shortness of breath at rest, necessitating 6 assorted inhalers, including nasal and tracheo-bronchial steroids. He experienced heart failure with edema of the lower limbs. The strokes left him with some permanent left-sided weakness, migraine headaches, and double vision. For years he has been on a multiplicity of antibiotics - a month without any was considered a “Good Month”! His Kidneys began to excrete albumin, and his BUN and Creatinine elevated as he approached renal failure that would require Dialysis. Because of the seriousness of his combined health problems, he “believed this would prove TERMINAL in a short period of time”. He became severely depressed because of his condition, and by what it was doing to his family. Despite what he could find on the Internet, and despite the efforts of 12 Doctors and Specialists, nothing seemed able to alter the downward trend of his health. He had “given up ALL HOPE, and was making preparations for his funeral”, when he was introduced to Glyconutritionals. After some Internet research he decided as a last resort to try some - “not expecting “ANYTHING” to happen . After all, nothing else had helped”. 3 months later the vision was improving, the ulcers of feet and legs were healed, the pain, swelling, weakness (including the left side stroke weakness), shortness of breath, and angina no longer were a problem. He was off all 6 inhalers, including steroids, and his arthritis was all but gone. He is able to walk without depending on the scooter or a cane. The Migraine has resolved, as has a chronic sinusitis, and he has not needed any more antibiotics. Blood pressure now averages 130/85 The albumin is no longer found in his urine, and the creatinine levels have not increased, indicating stable renal function rather than the previously noted progression. He lost to 280 lbs weight, and continues to lose fat and regain muscle mass. . The Insulin has been reduced to 10-50 units daily of Regular, with Ultra-Lente 60 units each Am and PM . The blood sugars are running 105-125, and the Glycohemoglobin (A1c) is now an incredibly low 5.1 (a measure of the biological level of glucose saturation of the Red Blood Cells. Very, very good!) He has admittedly not paid enough attention to his diet, and could no doubt reduce his weight and Insulin further by following a low glycemic diet, and, now that he is able, he is starting to do more exercise. His severe depression is no more, and best of all, to quote him, “I NOW HAVE HOPE, WHERE THERE WAS NONE! I am amazed at the changes that are occurring-some fast, some slow, some not yet, but things ARE IMPROVING!” Maxine is a 65 year old housewife who had Breast Cancer in 1984, treated with bilateral mastectomy . The cancer recurred in the abdomen and stomach 13 years later, for which she received 6 chemotherapy treatments in 1997. These were very poorly tolerated, and did not improve her condition. She developed obstruction of colon, necessitating a colostomy; and blockage in the stomach resulting in abdominal swelling, loss of appetite, and rapid weight loss. She was told there was nothing more to do, and Hospice was utilized for pain control with injections of narcotics, with expectation of death within 6 months. 3 months passed, with a downhill course. She and her husband did not give up, and sought help from herbs and whatever anyone might recommend, but without benefit. Glyconutrients were offered to her, and in desperation she began to take them. Within 2 weeks she was out of bed, going to Church, and a week later she insisted on going to a garage sale! She is now up and around, doing housework and the cooking, enjoying eating, in little pain, and the abdominal swelling has disappeared. Praise God! Such RESULTS as these, and now many others, I have not seen before in my 60 years as a Doctor!! Glyconutrients are fully documented to be safe, non-toxic, do not interfere with Rx drugs, and they work! Admittedly, no one thing is 100% - there must yet be some more unknown essentials, as well as the other known essentials: oxygen, water, and food: amino acids, fatty acids, carbohydrates, vitamins, minerals, trace elements. None of those are now apparently deficient within our current diet and traditional supplements - except 6 of the newly-recognized 8 essential monosaccharides! The only things that convince most of us Doctors are CONSISTENT, SAFE, RESULTS. We have all been led down the primrose path with promising new drugs, approved by the FDA, and seen them withdrawn from the market 6 months later because of dire effects on the liver, kidneys, bone marrow, GI tract, and/or pregnancy. How many more do we daily prescribe which result in only occasional "idiosyncratic" lethal effects with approved doses within the acceptable risk-benefit ratio? (but over 106,000 in the year 1997 died in hospitals from reactions to properly prescribed and taken drugs, as reported in JAMA July 26, 2000. This is the fourth leading cause of death in the US, outnumbered only by: Heart Attacks, Cancer, and Diabetes). It has happened in my practice, as it has in yours and every other Doctor who prescribes for patients. It has been devastating enough to me and you, but how much more so to the patients and their families! For them it is 100%! Carbohydrates were always acknowledged to be just for energy. Not any more!! Of the 200 known simple saccharides), there are 8 now recognized to be essential to all cellular function. They are glucose, galactose, mannose, xylose, fucose (not fructose), N-acetylneuraminic acid ( also called sialic acid), N-acetylglucosamine, N-acetylgalactosamine. Six of these “eight essential monosaccharides” are universally lacking in our diet, because of soil depletion, green harvesting, processing, preservatives, and overcooking. Fortunately our bodies can make the other 6 from glucose and galactose, if everything is all right! Obviously, everything is not all right if the body has a Health Problem, whether from infections; toxins in our environment: the air we breathe, the food we eat, the water we drink; stresses in our lifestyle; deficiency of a necessary enzyme, vitamin, co-factor, trace mineral; or a genetic defect, in the 15 or more stages, plus much energy, to convert one (available) sugar to another! Currently, the most important one of all these “essentials” is the one that is missing! And “essential” means indispensable: without it, the body is dysfunctional, sick or dying! There are many new studies, Double-Blind, Placebo-Controlled, with enough numbers to be Statistically Significant, as we are so used to seeing, but these are years away from being reported. Many are not subject to double blinding or placebo control, such as near-terminal Cancer cases, Genetic Disorders with progressive downhill course, and Immune Dysfunction diseases which are epidemic, overwhelming us over the past 2-3 decades, and for which we have no cure --- nor even satisfactory or safe relief of the symptoms, with our conventional therapy. Asthma, Lupus, Hepatitis C, Rheumatoid Arthritis, Osteoarthritis; Cancer, ADD-ADHD, Fibromyalgia, Diabetes types I and II, Chronic Fatigue Syndrome, Multiple Sclerosis, AIDS, Ulcerative Colitis, Crohn’s Disease, Down Syndrome, Muscular Dystrophy , ALS (Lou Gehrig’s Disease), are just a few examples. Administration of Glyconutrients has resulted in improvement or remission, without any harmful side effects, in each of these conditions, as documented in reports or publication in peer-reviewed Medical Journals. What could possibly be the common denominator of all these? Immune System Dysfunction! Why? Something is missing! Glyconutrients are not a treatment, mitigation, or cure for any disease, but if these food supplements are supplied in the diet, the body can heal itself of virtually anything wrong! (But not grow a new tooth in an adult if one is pulled, nor a new limb if it is amputated. That is not in our DNA! It is, however, in the DNA of Earthworms cut in half, Sharks who lose a tooth, and Centipedes who lose a leg! These 8 monosaccharides are in and on the surface of every cell in the body. They are necessary as the glyco of glycoproteins on the surface of every cell, as transmitter or receptor, of all the vital reactions between cells: defense, repair, regulation, nutrition, and apoptosis, (the programmed death and recycling of all cells). Every cell in the body (100 Trillion or so!) is replaced at different rates: (e.g. WBC, 6-7 days; RBC's, 3-4 months; DNA and most Internal Organs, 6 months; Bone, 9 months to years; Brain and CNS, 14 months). These monosaccharides are present as a substrate in the endoplasmic reticulum, and as building blocks for the glycosolation occurring in the Golgi apparatus of cells, forming glycoproteins, proteoglycans, glycolipids, and the N- and O- and GPI- anchored linkages (Nitrogen- ,Oxygen-, and Glycosylphosphatidyl-inositol- linkages). This is all under control of the DNA as the blueprint, and mRNA, as the message. The glycoproteins translate the messages and send chemical signals (cytokines) to the appropriate receptors, (also glycoproteins) to facilitate the proper action at the cellular level. This is the Universal Code of Life, equivalent to the Microsoft Operating System, which runs all computers! This is extremely complicated and has to be, not 99.9999% perfect, but 100%, or there is dysfunction, disease, or death! I have studied it intensively, still know so little, but yet enough to be awed and excited by what I have witnessed! Supplying Glyconutritionals in the diet has enabled the body to modulate the immune system: elevate those elements that are too low, as in Cancer and AIDS; reduce those that are too high, as in autoimmune diseases; or do both, as in most of the immune dysfunctions!! This Modulation had been considered impossible-something never before seen in Medicine. The Natural Killer Cells, necessary as the first line of defense against Infection and Cancer, are reduced by 30 % in even the “normal” population in the past 2 decades, and are further falling by 3% per year. No wonder 250,000,000 of the US population are suffering from some form of acute or chronic disease! These NKcells are restored to normal numbers in those receiving Glyconutrients. How? I do not know! But the body knows! Thank God! Glycoprotein interactions generated the actual specific chemical messages sent. This is what Drs. Bill H. McAnalley and Reg. McDaniel contributed in their research on carbohydrates in the past 15 years- then scoured the globe for plant sources of the missing monosaccharides. They were identified, isolated, purified, and combined into a powder as a Nutraceutical: -a pharmaceutical-grade natural food concentrate. Dr. Robert K Murray, Senior Editor of Harper's Biochemistry (Appleton and Lange,1996) wrote the chapters 56 through 65 on: Glycoproteins; The 8 Essential Monosaccharides; The Extracellular Matrix; Muscle Metabolism; The Immune System; etc. I now have the 2001 revision, and am poring over the awesome biochemical reactions, newly-discovered, in this explosively growing segment of Biochemistry: Glycoscience, Glycobiology, and Glycomics! I will ask you, Doctor, if I may, "How did you advertise when you started your Medical Practice? Newspaper? Radio? TV?" "Or Word of Mouth from satisfied Patients?? I can guess!!! So did I! Don't knock Word of Mouth! We do not sell products, but educate and introduce the good news to those we love and want to help, who then can order these Glyconutrients wholesale from the only company who can supply all of them, have them shipped directly to their home; to be taken as a complement to conventional Medical Care. We and they see benefits more safely, more completely, more consistently, and less expensively, than we have ever seen in our lives before! And they, in turn, will share the good news with others who are suffering from the effects of these deficiencies! I am now retired, but I can’t deny my love for Medicine, nor yet ignore the recent monumental advancements in the Science of Nutrition, and especially the role of monosaccharides in the formation of glycoproteins, so vital in the function of the cells of our body. At age 87 I am starting a new career (nay, Mission!) to share with everyone I meet, this epochal Nutritional Breakthrough, and its effect on the immune function. Medicine has advanced beyond the Blood-letting, Leeches, and Maggots treatment of disease to Immunizations, Wonder Drugs, incredible Surgery, Organ Transplants, and Genomes. We have great expectations from the latter, but the promised wondrous cures are yet years away from application, and even the initial Genetic modifications are fraught with the same old side-effect complications as other synthetics have exhibited. The body is programmed by God to utilize whatever it needs from our diet, and is not about to change. Stem Cell Cloning is far from perfect, although it must be invariably perfect, and subject to the same responses to nutritional deficiencies as those we have found so refractory-until the missing Glyconutrients are supplied. Glyconutrients are already available here and now, safe and effective, awaiting but the eventual universal recognition by all Health Professionals: that this New Nutrition is the Keystone of Prevention and Wellness, as our New Focus in the Practice of Medicine, versus the traditional paradigm of Treating Sickness with Drugs). This new Paradigm in Medicine did not originate in the traditional “A Drug Cure for Every Disease” concept of Pharmacology, nor yet by the Nutritionists. This is a “Disruptive Technology”, comparable to the displacement of wax and vinyl phonograph records with magnetic tape, and this in turn by digital CD, each of which was birthed by a totally unrelated industry. Likewise, was the obsolescence of the watch and clock by the quartz crystal; and the mechanical typewriter by the electric, and this, in turn, by the word processor of the computer, again an upstart industry. The new Biochemistry: Glycobiology, Glycoscience, Glycomics: Glyconutrients! For those who might be interested in my “pedigree”, I have BA and MD degrees (1939) University of Colorado: (Phi Beta Kappa, and Alpha Omega Alpha, Honor Medical Society). Lt. Col. Medical Corps. Army of US, WW II; Diplomate American Board of Internal Medicine; Fellow American College of Physicians (FACP); Fellow American of College Cardiology (FACC); Clinical Associate Professor of Medicine, University of Oklahoma School of Medicine, Tulsa; Past Chairman Medical Section, St John Medical Center and of St. Francis Hospital; past Vice-President Medical Staff St. John Hospital; past President Medical Staff St. Francis Hospital. I couldn’t blame you if you thought me a Kook,--- but do please be open-minded, for your own sake, and for that of all your patients. And in so doing you will honor the aphorism of that wise old Doctor, Hippocrates, the Father of Medicine, whose first concern with his patients was “Primum non nocere.” Above all, do no harm! And his next was “Let your food be your medicine, and let your Medicine be your food.” What goes around comes around! Rayburne W. Goen, Sr. MD Letter Two: An Open Letter From Rayburne W Goen, MD, FACP, FACC. Saturday, August 3, 2002 An Open Letter: Carbohydrates have always been considered as “energy food”, but not until 1994 was it discovered, and in 1996 proven, and recognized in Harper’s Biochemistry Textbook, that there are eight monosaccharides (super carbs), essential to maintaining good health. “Essential” means indispensable, the body cannot make it, and without it you are sick or dying. I believe this will go down in history as the most significant health discovery of the century! It will rank with or above the discovery of the essential amino acids, (protein building blocks); the vitamins and trace minerals; the essential fatty acids; penicillin; cortisone; and chlorthiazide, (the first effective blood pressure drug)! Note that all but the last 3 are nutritional discoveries. These eight glyco-nutrients (sugar-foods), the essential monosaccharides, combine with proteins to form glycoproteins on the surface of every one of the trillions of cells in the body. We know them as communication agents: either transmitters or receptors.. They constitute the operating system for all cell function! The “Microsoft Windows” of every cell, for the immune system-which must communicate to function well or we are sick -- or dead! (They communicate the needs of cell repair, defense, nutrition , recognition as “my own” or “enemy”, hormonal regulation, and apoptosis: programmed cell death, disposal, and replacement of all cells). What is amazing is that one little sugar molecule, misprinted or omitted, by damage from virus, bacterial infection, fungi, pollutants, toxins, stress, or gene defects, can make as much difference as if you telephoned 1-918-492-023 instead of 1-918-492-0232 :(would not transmit!): Or 1-918 492-0233 (not me: an alien!). Important? Yes!! Do you realize, for example, that human blood types differ in only one small detail: Galactose is the terminal “address” on the glycoprotein on the surface of the type B red blood cell; N-Acetylgalactosamine on the type A . Transfusing a Type A patient with Type B blood (or vice versa) results in a very acute immune-type reaction: --death! What is the significance of this? Only two of these essential monosaccharides: glucose from sweet foods and carbohydrates, and galactose, from dairy products, are found in our diet today! Why?? During the past 25 years, our food supply has changed from home gardens, or local truck farms, with tree-or vine-ripened fruits and vegetables, to such industrialization that now almost all fruits and vegetables are raised on large commercial farms. The soil on these farms is depleted of nutrients and minerals. The soil is sprayed with toxic chemicals to kill weeds and insects; fertilized with nitrogen, potassium and phosphorous, which still makes plants grow, but lacks vital trace minerals. Then, to make it worse, produce is harvested green, so it can be transported across the country or ocean and withstand shipment. Because the produce is not allowed to ripen on the vine, our fruits and vegetables do not have all the phytochemicals that the American Cancer Society says are so important in building our immune systems. ( Phytochemicals are not produced in our plants until they are fully vine-ripened ) We further deplete our grains, source of some essential sugars, by hulling and removing the germinal portions of wheat, rice, and oats etc. The result of all this is that SIX of the eight ESSENTIAL monosaccharides are no longer in our diet! We also deteriorate our foods by processing methods, preservatives, and over-cooking. Fortunately, our body can make the missing 6 super carbs by a complicated, energy-consuming process, using 15 or more reactions, each requiring a specific enzyme-- if everything is working perfectly! Obviously everything is not always working perfectly or there would be no health problems! Note: The most important essential to life or health is the one that is missing! The Natural Killer cells, a type of lymphocyte, recognizable in the blood, and which are the first line of defense against infections, toxins, and cancer, have been reduced 30% in the average “well” American in the past 16 years. Why? Partly because there are now 300-400 new chemicals, which the body recognizes as toxins- in every cell of our body, that were not there before 1948! That explains why, in the past 20-30 years, as nutrients in our diet have decreased, and toxins in our air and water have increased, that our body’s defense system has begun malfunctioning .This is evident in the increasing incidence of disease and cancer. The following are the 1997 statistics on the major causes of death in the US, as reported in the Journal of the American Medical Association July 27, 2000: 1. Cardiovascular [Heart and blood vessel disease], 50% of all deaths (also now considered as a possible complication of remote Chlamydia, Coxsackie, or Herpesvirus infection, with subsequent immune dysfunction). 2. Cancer, increased from #8 in 1973 (a result of a failure in the immune system to recognize and destroy mutated cells, which then multiply and “take over”): 30 % of all deaths,,, and predicted to be #1, (70 %) in the next 10 years. 3. Diabetes 12 % and gaining, (an autoimmune disorder in type I, destroying cells that produce insulin); and an immune dysfunction in type 2: some receptors do not recognize insulin, necessary to admit glucose into cells. 4. Adverse reaction to properly prescribed Pharmaceutical drugs! 106,000 such hospital deaths in 1997, not involving wrongly prescribed dosages, errors in filling, deaths outside the hospital, or suicides! Put this in context with 12,000 deaths the same year by auto accident involving alcohol. Which has received the most publicity? Why?? Finally, it has been demonstrated that oral administration of these eight glyconutrients (super-carbs) is totally non-toxic in any amounts, does not interfere with bodily function like drugs do. And results in restoration of the cell’s ability to communicate its needs, so that the body can defend, regulate, nourish, repair and cleanse itself as God intended. (Human mother’s milk contains 5 of these essentials: -- no other animal’s provides more than 2!) Breast feeding of infants confers lifelong benefits, which no other substitute or formula thus far can match! This discovery is not a medicine, to be prescribed for treating or curing a specific disease, but rather a supplement of vitally necessary monosacccharides that are missing in our diet today. When they are put back into the body, the body can then do what God designed it to do: heal itself. A few of the disorders which have been shown (in reports or published articles in Medical and Scientific journals) to be benefited or restored to normal health, (without interfering with appropriate drug therapy as indicated ) are: Asthma, Rheumatoid Arthritis, Osteoarthritis, Systemic Lupus, Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Peripheral Neuropathies, Attention Deficit-Hyperactivity Disorder, Down Syndrome, Diabetes, Muscular Dystrophy, Cancer, Ulcerative Colitis, Crohn’s, Alzheimer’s, Parkinsonism, Hepatitis C, and AIDS, as well as a whole host of others. What is the common denominator of all these apparently unrelated diseases? Dysfunction of the immune system. Why? Failure of communication between cells. Why? A missing essential monosaccharide in the surface Glyciprotein of a cell. Amazing to me was the dramatic response of Lupus by restoring these glyconutrients.. Lupus is a disease from an overactive immune system, when the immune system actually attacks its “own” body cells. (“mis-communication”) On the other hand, I have seen reports that taking glyconutrients dramatically increases low immune function as in AIDS or Cancer This is called “modulation”, reducing the too-high and elevating the too-low, as in many diseases which exhibit both types of dysfunction. Never before have Medical Doctors seen this, or even thought it was possible. This was proven in numerous experiments conducted at “neutral, third party” research laboratories, and clinical cases reported in peer-reviewed Scientific Journals from all over the world. Nutrition has not been, until now, a part of USA traditional Medical School curricula for treating or preventing chronic illness. This is changing as of 1999, with the New Nutrition: Prevention and Wellness, rather than Sickness and Drug Treatment, as the new Focus of Medical Care. Enough of “Micro-Nutrient Biology 101"-even though not mentioned is the burgeoning problem of Overweight, and the frightening and rapidly-increasing microbial resistance to antibiotics, that are now getting worse by the day. “Antibiotic resistant” means our most powerful drugs are no longer working against infections with these organisms. They develop Immunity! In addition, there are “new” viruses and microorganisms surfacing, for which we have no effective antibiotic. The bottom line is: everybody in the world desperately needs these particular missing monosaccharides, whether they are now sick, or “healthy”( = not yet sick !). Believe me, preventing infections, diseases , and especially cancers is a lot less expensive and more efficient and satisfying than trying to treat symptoms with dangerous drugs, with never or rarely a cure! For years, I have felt helpless and frustrated, when patients would come to me for advice and relief of their pain and suffering, and I was unable to prescribe a safe drug that would relieve or cure them. I, as a Doctor, trusted in the axiom “For every disease, a cure.” I realize now that was not God’s way. In my whole life as a Doctor, I have never seen anything so AWESOME as I am now seeing : that taking these nutrients orally has enabled the body to heal itself of almost any disease known!! (Nothing, however, is 100% in the real world!) I am so excited that now, in my retirement, I have an opportunity to introduce this, and thus educate and help benefit more people, safely, more fully, in a much shorter time, than ever I did in my 60 years of Practice in the Medical profession!! WOW! I urge you to look seriously at this discovery, which, the way it developed, had to be a revelation from God. Check it out. [This Company] is the only source of an oral form of these eight monosaccharides, any combination of which is “composition patented or patent-pending” worldwide.. [The Company’s] Science and Research labs are second to none in the field of pharmaceutical grade nutrients (nutraceuticals) . There are many peer-reviewed studies available, as well as independent studies reported on Medline on the internet. There are now thousands of scientific articles documenting the validity of this discovery in the Medical Journals. You owe it to yourself and your family to see what is available to you for protecting your health in a very unhealthy world. To your Health, Happiness, and Good Fortune!!! Rayburne W. Goen, MD Back to Amorganic Home Page

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